I try to put this in perspective - Personally, and probably for many fans, the desire to resist trading him is because of another player that also had a lot of struggles early in their career: David Ortiz.
Ortiz was released because he would have cost a paltry ~$2m a year, and got nothing in return. We had roughly the same MLB sample size with Sano as we did with Oritz. Sano's MLB story still needs to be written, but Ortiz's was rare in becoming one addition on a relatively short list of first-time ballot hall of fame inductees (I had to look it up - https://www.baseball-reference.com/bullpen/First_Ballot_Hall_of_Famer)
My point is this - we may be gun shy, but the odds of making a trade or cutting Sano and having the results play out anywhere close to the way it did for Ortiz are minuscule*. The team has proven they can win without him, and they shouldn't take away playing time for the current players to make room for him.
* of course, leave it to the Twins to let someone go and have them turnaround their career in to one that is worthy of the HoF.