I anticipate there will be enough demand for Joe Ryan this offseason that they will receive an offer they can't refuse. I am not sure that is true for Lopez, so they may hang onto him for another year. They may even hang onto Lopez for two more seasons and give him a qualifying offer. That is making an assumption that the next CBA has similar rules for qualifying offers. If the QO goes away, they need to trade Ryan, Lopez and Ober before 2027.
My guess is
Ryan is traded this offseason
Ober is traded at the July trade deadline
Lopez is traded next offseason or the following July deadline
Then we can all discuss which one of the Twins still remaining in 2027 is next to be traded. Lather, rinse, repeat.