If they want Ryan up at the start of next year, he'll pitch in MN this year to get acclimated. If they don't do that, I would bet money he's not on the opening day roster next year.
He's 25....no need to baby him. Now, he might need work on certain pitches, that's different. But, there is no reason to protect him at this point.
Me? I'd call him up to get him acclimated to the majors. But I don't know what they'll do.
I am not worried about losing a fringe player at this point, so I'm not worried about the 40 man.