http://www.beyondtheboxscore.com/2009/3/17/795946/optimizing-your-lineup-by The takeaway from this is as follows: Here's how the lineup spots rank in the importance of avoiding outs: #1, #4, #2, #5, #3, #6, #7, #8, #9 This would mean your #3 hitter should be the player most teams now probably put at #5 or #6. I have no idea if any manager or coach has ever put this to extended use but it would be an interesting experiment. I'm surprised the stat-heads here haven't investigated and reported on this. Or maybe they have somewhere in the archives. To address Chief's thought, of course any team would like a 2009 Joe Mauer or a 2006 Justin Morneau in an important spot in the batting order, whatever spot that happens to be. But pitching is now and ever shall be the most important aspect of the game. The best pitchers can shut down the best hitters. The 2006 Twins went 69-33 over their last 102 games. The main reasons: Santana won the Cy Young even though he was our #2 starter for much of that stretch and the bullpen was a brick wall.