Barring trades or injury, I don't really see a lot of changes to the roster regulars. I think Kirilloff will eventually do enough damage in AAA to get called up and take over 1B. That likely pushes Larnach, Kepler or even Gallo out.
I'm not worried about Lee so much. They can afford to be more patient with him unless he's just destroying the minor leagues. I think Lewis is a bigger wild card since he's already had a taste. That all depends on how he comes back from his knee injury though.