In fairness, some billions are made due to the incredible leverage that is possible in today's global economy. The effect on the people you mention is the same, but they aren't specifically targeted. For instance when Amazon.com got big, and made their founders rich, a lot of middle-class jobs went away because shopkeeping suddenly wasn't as valuable. The scale of this is something Adam Smith simply had no way of anticipating, and yet our economic theory is still guided by his world of blacksmiths and general store owners.