Gardy seemed pretty upset with Matt Maloney last night, so I could see Maloney and Jeff Gray (more walks than strikeouts) getting designated for assignment. Liam Hendriks needs more time in AAA.
I see the Twins bringing up only two pitchers, most likely Jeff Manship and Scott Diamond, since they are on the 40-man roster already. Kyle Waldrop could be another possibility, once he completes his rehab assignment.
For batters, Clete Thomas is most likely to be DFA, due to his inability to make contact. I don't know who the Twins will want to bring up to replace him.