I guess it feels like trading Berrios for minor-league pitchers is almost certainly giving up on 2022. It seems really unlikely that you would get starting pitching that would be better than Berrios would be in 2022. Once in a while you'll get a John Smoltz or Dwight Gooden who is an ace starting pitcher as a rookie, but it's really rare.
Here are the only rookie pitchers who are better than Berrios in terms of Fangraphs WAR this year: Trevor Rogers (MIA) at 2.8 WAR, Ian Anderson (ATL) at 1.9 WAR. Berrios is at 1.8 WAR. In the last full season, 2019, there was no rookie starting pitcher who equaled Berrios's 4.3 WAR.
So, it's possible to improve, but you would have to make a really good trade and probably get lucky. The most likely way you end up with a better pitcher than the 2022 Berrios is if Berrios gets injured, which is certainly possible, but then it's just as likely that the rookie replacement gets injured.
If we don't need hitters for 2022 (I'm skeptical about that, but maybe it's true), then I might hold Berrios rather than trading. Maybe we can trade Nelson Cruz and Michael Pineda for some good 2022 arms (probably bullpen arms - it think it's more common to find rookies who can handle relief roles), put them together with Berrios and some free agents (not that 2021 has given us much reason to believe in our ability to find pitching via free agency), and have enough pitching to contend in 2022.
Or, maybe we need to give up on 2022 and trade Berrios for a vanload of great low minors pitching prospects.