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George Alex Tsamis was born on June 14, 1967 in Campbell, California.

The Minnesota Twins selected him in round 15 of the 1989 MLB Draft out of Stetson University. He spent time as both a starter and a reliever in the minors. The Twins called Tsamis up to the big leagues on April 25, 1993 to work out of the big league bullpen.

He pitched one season at the Major League level, going 1-2 with a 6.19 ERA across 41 appearances and 68.1 innings. His lone win came on May 26th in a 12-11 shootout win over the Oakland Athletics. He also picked up a save against the Athletics on August 14th. Minnesota released him during spring training in 1994. Tsamis pitched in the Seattle Mariners system during the 1994 season, but spent most of the year injured.

The Los Angeles Dodgers signed Tsamis as a replacement player during spring training in 1995, which barred him from future MLBPA membership. He continued to pitch in independent leagues until 1998, but never resurfaced at the big league level.

Tsamis has been a long time independent league manager since retiring. He won Northern League championships with the New Jersey Jackals in 2001 and 2003, before embarking on a long stint managing the St. Paul Saints. Tsamis managed the Saints from 2003 until 2020, when they left independent ball to become a Twins minor league affiliate. During his tenure, the Saints won league championships in 2004 and 2019. The organization retired his #22 in 2021.

As of 2025, he is managing the Kane County Cougars of the American Association. He led them to an American Association championship in 2024.


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