Any one of DeVries, Hermsen, Bernier, Ramirez, and Clete could be removed from the 40-man if they wanted to give Sano some MLB time. The only concern could be Rule 5 time, but they should have enough spots to protect guys between removing those 5, Morneau's free agency, and the possibility of trades both now and then. I'm not saying they absolutely should call him up, but I do believe they should do whatever they think would be best for the development of Miguel Sano and not worry about the roster spot.