Twins hitters taken in top 5 rounds since 2000: 2000: Tag Bozied, Edgardo Lebron 2001: Mauer, Jose Morales 2002: Span, Michael Thomas 2003: Matt Moses, John Woodard, Brandon McArthur 2004: Plouffe, Mark Robinson 2005: Henry Sanchez, Andrew Thompson, Paul Kelly, Michael Moore, Steve Tolleson 2006: Parmelee, Benson, Garrett Olson, Whit Robbins, Devin Shepherd 2007: Revere, Danny Rams, Angel Morales 2008: Hicks, Tyler Ladendorf, Daniel Ortiz, Nicholas Romero 2009: Derek McCallum, Tobias Streich 2010: Niko Goodrum, Eddie Rosario, Nate Roberts 2011: Levi Michael, Travis Harrison, Tyler Grimes 2012: Buxton, Adam Walker I cut it off at first 5 rounds, but the line could be drawn anywhere depending on your preference. I'm not sure that I'd say it's primarily guys from other organizations that have struggled. In the span of 2000-2007 (2008 class now just rolling into the big leagues with Hicks) the Twins only got, by my count, 7 hitters at the top of the draft who ever saw big league ABs. Of the seven, four of them are Plouffe, Parmelee, Benson, and Jose Morales, who are either still relatively unknown commodities or known non-commodity Jose Morales. Minus the jackpot of taking Mauer at #1, they have gotten two guys who profile as MLB regulars, and one of them is Ben Revere, whose ideal position would probably be a 4th OF on a good team. That's out of 23 non-Mauer hitters taken. None of the ones I see on the list ever went on to do anything with a different organization, either. I'm not sure how you'd define "bust", but "being out of baseball without ever sniffing the high minors" would be a good start, and many, many of these guys fit that bill.