Say what you want about Plouffe, he's more valuable to the organization at this point in his career than Mauer is. Bench or trade Mauer (even if you have to eat virtually all of his salary - throw Nolasco in, too, and get some bullpen depth). Call up Vargas and start Sano at third. Use Plouffe as your corner utility infielder. If you keep Mauer, he can DH, play a little first base and even pick up some time in the outfield if absolutely necessary. Getting rid of Plouffe is not a good option.