I think Liriano could likely perform similarly to his 2010 season, as he's not going to be suffering from dead-arm. Baker, hopefully, will continue right where he left off last year, and I think he has a pretty good chance of that.
As for Blackburn, he could either get injured again and perform terribly, or he could be reasonably effective, like in the early 2011 season. If he doesn't have his control or command due to injury, he's just going to give up home runs and walk too many, like last year. I think that, with the use of his slider back, as well as a better changeup than in 2008 or 2009, he could be the least of the Twins' worries.
Pavano and Marquis might not look so great, though. While Liriano/Baker/Blackburn have upside this year compared to their last two seasons, I'm not too sure about the older two, but I'd err on the side of caution.