La Velle lists five questions for the Twins, but they're spring training, not season related. Instead of Mauer's workload, I'd add something about the bullpen, which looks to be full, but not especially effective. I kind of like #4...

4 TABLE SETTERS
The Twins appear to have a dangerous middle of the order if everyone stays healthy. But who will ignite the offense? It looks like whoever plays center field will lead off and whoever plays second base will bat second, but will someone step up and show table-setting ability? Will Joe Mauer have to bat second?
Chart: Five questions facing the Twins | StarTribune.com